Our Mission

The Phagebiotics Research Foundation studies and promotes medical and veterinary applications of bacteriophages in the treatment of bacterial disorders.

Our Principles

• We are focused on development of bacteriophage therapy as a tool to combat the growing issue of antibiotic resistance.

• We support projects that provide the required knowledge and infrastructure foundation to carrying out physician-initiated controlled clinical trials both in the US and collaboratively with colleagues in foreign countries.

• As a nonprofit research foundation focused on science and community need, findings supported by our efforts will be publicly available for use to further develop the field.

Our goals

• Supporting collaborative research that helps further clarify the safety and efficacy of phage therapy for key applications.

• Bringing together the medical and scientific communities across countries and disciplines in order to coordinate research efforts for greatest impact.

• Collaborating closely with other interested parties working towards widespread regulatory approval of phage based therapeutics.

• Developing a forum for the establishment of evidence based phage therapy clinical practice, and the clinical research needed to answer key “best practice” questions.

Education

• Supporting and providing phage therapy education for medical, scientific and general audiences.

• Helping to develop the medical and pharmaceutical infrastructure needed for the application of phage therapy.

• Developing a forum for the establishment of evidence based phage therapy clinical practice, and the clinical research needed to answer key “best practice” questions.

Conditions we are currently focused on

Treatment of Diabetic Foot Infections: Infections of the bone (osteomyelitis) after failure of antibiotics and appropriate surgical care. For such patients, the standard treatment is amputation but we and others have demonstrated that such infections can be treated with phage and the need for amputation greatly reduced.

C. difficile Infection and Antibiotic Resistance: Phage are critical to the problem of antibiotic resistance and the dysbiosis that leads to infection with C. difficile and other multi drug resistant organisms (MDROs). For patients treated for recurrent C. difficile infections the case of “phage therapy” is in the form of the fecal Microbiota Transplant (FMT).